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商品描述
More Information
Alternate Name/Synonyms
Framycetin sulphate; Neomycin Trisulfate Hydrate; Neomycin B sulfate
SKU
N-1053
CAS #
1405-10-3
Chemical Name
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol;sulfuric acid
Chemical Formula
C23H46N6O13 • 3H2SO4
Molecular Weight
908.9 Da
Appearance
White to yellowish powder
Purity
N/A
Solubility
Soluble in water.
Melting Point
N/A
Preparation
N/A
Storage Temp
20°C, desiccated
THERAPEUTIC AREA
Bacterial infections
USE
Neomycin Sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor which inhibits PLC (Phospholipase C) via binding to inositol phospholipids. It is used as a selection agent for prokaryotic cells that have been transformed using the selectable marker gene (neo), and to study ototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts, and extraction of Nuclear Phosphatidylinositol 4,5-Bisphosphate-Interacting Proteins.
Merck Index
13.6482.2001
RTECS
QP4375000
Handling
Use only under a chemical fume hood. Wear personal protective equipment. Avoid dust formation. Do not get in eyes, on skin, or on clothing. Do not breathe vapors/dust. Do not ingest.
Certificate of Analysis 1
N-1053, J1101.pdf
Certificate of Analysis 2
N-1053, J1065.pdf
Certificate of Analysis 3
N-1053, H1429.pdf
