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商品描述
More Information
Alternate Name/Synonyms
CHAPS
SKU
C-1019
CAS #
75621-03-3
Chemical Name
3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate
Chemical Formula
C32H58N2O7S
Molecular Weight
614.9 Da
Appearance
White solid
Purity
≥98%
Solubility
Soluble in DMSO or DMF
Melting Point
157 °C
Preparation
N/A
Storage Temp
Room temperature
THERAPEUTIC AREA
Not Available
USE
CHAPS is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons. CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions and is electrically neutral. CHAPS is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. The critical micelle concentration of CHAPS is 6-10mM.
Merck Index
13.2052.2001
MDL NUMBER
MFCD00012116
CHEMACX
X1016609-1
INCHI
InChI=1S/C32H58N2O7S/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41)/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1
SMILES
C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #"S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Ensure adequate ventilation, especially in confined areas. Use personal protective equipment as required. Use with local exhaust ventilation. Do not breathe dust/fume/gas/mist/vapors/spray. Handle in accordance with good industrial hygiene and safety practice. Corrosive hazard. Wear protective gloves/clothing and eye/face protection.
msds 1
C-1019, CHAPS, SDS, diamond format.pdf
Certificate of Analysis 1
C-1019, J1303.pdf
Certificate of Analysis 2
C-1019, J1219.pdf
Certificate of Analysis 3
C-1019, J1051A.pdf
