多克隆抗体

Glucocorticoid receptor多克隆抗体

货号:E-AB-30289
抗体英文名:GlucocorticoidreceptorPolyclonalAntibody
应用范围:WB
宿主:Rabbit
适应物种:Human,Mouse,Rat
克隆性:
保存条件:Storeat-20℃.Avoidfreeze/thawcycles.
亚型:IgG
免疫原:RecombinantProtein
规格:30μL/60μL/120μL
Overview
SynonymsNR3C1,GRL,Glucocorticoidreceptor,GR,Nuclearreceptorsubfamily3groupCmember1
SwissprotP04150
GeneID2908
SourceRabbit
ReactivityHuman,Mouse,Rat
ImmunogenRecombinantProtein
ApplicationWB
RecommendeddilutionWB1:1000-3000
Concentration1mg/mL
ClonalityPolyclonal
ResearchAreasCancer
 
Properties
IsotypeIgG
PurificationAffinitypurification
ConjugationUnconjugated
CalculatedMV86kDa
ObservedMV80-97kDa
StorageinstructionsStoreat-20.Avoidfreeze/thawcycles.
StoragebufferPBSwith0.02%sodiumazide,50%glycerol,pH7.4
Background
 
Receptorforglucocorticoids(GC).Hasadualmodeofaction:asatranscriptionfactorthatbindstoglucocorticoidresponseelements(GRE)andasamodulatorofothertranscriptionfactors.Affectsinflammatoryresponses,cellularproliferationanddifferentiationintargettissues.CouldactasacoactivatorforSTAT5-dependenttranscriptionupongrowthhormone(GH)stimulationandcouldrevealanessentialroleofhepaticGRinthecontrolofbodygrowth.Involvedinchromatinremodeling.Playsasignificantroleintransactivation.Involvedinnucleartranslocation.

Image


WesternBlotanalysisof1)Hela,2)Jurkat,3)HepG2,4)Mouseliver,5)RatbrainusingGlucocorticoidreceptorPolyclonalAntibodyatdilutionof1:2000.

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温馨提示:不可用于临床治疗。

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