MouseAnti-MICA/FITC流式抗体说明书

CatalogNumber:RS-0832R-FITC

Quantitysize:0.1ml（dilutewithpH7.40.01MPBSorantibodydiluent）

Background:TheMHCclassIchain-related（MIC）proteinsarerelatedtotheMajorhistocompatibilitycomplex（MHC）classIproteinswhichareubiquitouslyexpressedandmediatetherecognitionofintracellularantigensbycytotoxicTcells.TheMHCclassIchain-related（MIC）proteinsarerecognizedbyNKG2D,areceptoronNKandTcells,andpromoteanti-tumoractivity.MICA,amemberoftheMICfamily,iswidelyexpressedonmanytumors,anditistheMICA/NKG2Dinteractionthatisthoughttostimulatetheanti-tumorreactivitybyTlymphocytes.MICAispresentinvirtuallyeverytissueexceptthenervoussystem,suggestingthatMICproteinexpressionmayonlybeonecomponentoftheanti-tumoractivityoftheimmunesystem.

Function:Seemstohavenoroleinantigenpresentation.Actsasastress-inducedself-antigenthatisrecognizedbygammadeltaT-cells.LigandfortheKLRK1/NKG2Dreceptor.BindingtoKLRK1leadstocelllysis.

MICA/FITC流式抗体说明书Specificity:·anti-MICA/FITCisamousemonoclonalantibodyunconjugated

·specificforMICA/FITCofpig

·useforwesternblotting,ELISA,immunoprecipitationandimmunohistochemistry

·ProteinGaffinitychromatographypurification,purity:>95%

·Isotype:IgG

·molwt:43kDa

Application:·Flow-Cyt=1:50-200

·IF=1:50-200

·Optimalworkingdilutionsmustbedeterminedbytheenduser.

MICA/FITC流式抗体说明书Storage:Storeat–20ºCforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20ºC.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibody,theantibodyisstableforatleasttwoweeksat2-4ºC.

ImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications.