Product Specification:
| Alternative Name: | TRAIL receptor 1, Apo-2, CD261, DR4, Death receptor 4, TNFRSF 10A, TNF-related apoptosis-inducing ligand receptor 1, Tumor necrosis factor receptor superfamily member 10A |
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| Clone: | HS101 |
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| Host: | Mouse |
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| Isotype: | IgG1 |
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| Immunogen: | Recombinant human TRAIL-R1. |
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| UniProt ID: | O00220 |
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| GenBank ID: | U90875 |
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| Gene/Protein Identifier: | 8797 (Entrez GeneID) |
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| Species reactivity: | Human
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| Crossreactivity: | Does not cross-react with human TRAIL-R2, -R3 or -R4. |
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| Applications: | Flow Cytometry, ICC
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| Recommended Dilutions/Conditions: | Flow Cytometry (1:200)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
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| Formulation: | Liquid. 100µg in PBS containing 0.02% sodium azide. |
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| Handling: | Do not freeze. Protect from light. |
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| Shipping: | Shipped on Blue Ice |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | +4°C |
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| Scientific Background: | TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-κB. |
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| Technical Info/Product Notes: | ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 647N shows red fluorescence (λabs (max): 645nm, λem (max): 669nm, εmax: 120’000). |
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Enzo代理商，Enzo life science代理商，Enzo代理商2014年，Enzo life science一级代理商，Enzo life science最新代理商，Enzo life science生命科学试剂产品
西安凯新生物科技有限公司还是ENZO lifesciences公司中国区代理商，eBioscience公司中国区代理商，Biolegend公司中国区代理商，Ludger司中国区代理商，Peprotech公司中国区代理商，anaspec公司中国区代理商，CST公司中国区代理商，Prospec 中国区代理商，Innova Biosciences 中国区代理商，abcam代理商，BD Biosciences公司中国区代理商，Abnova公司中国区代理商，Cayman Chemical公司的中国区代理。
Enzo旗下共有Enzo，Biomol，Alexis Biochemicals，AssayDesigns，Stressgen等品牌，为生命科学研究者提供基因组分析，细胞生物学，翻译后修饰，信号转导，肿瘤和免疫学，药物筛选等相关领域的优质产品。Enzolife sciences 的标记技术和检测技术在科学研究和临床诊断这两个领域中处于领先地位。标记探针和染料的强强组合是基因表达分析，核酸检测，蛋白质生物化学研究与检测，分子生物学，细胞分析等研究领域中目标识别/验证和高容量分析实验的强有力工具。
ENZO life sciences 主要产品：Microarray Analysis(生物芯片分析类产品)、ModifiedNucleotides（带修饰的核苷）、Nucleic Acid Labeling Systems（核苷酸标记系统）、MonoclonalAntibodies、Human Papillomavirus、Identification Systems(人乳头状瘤识别系统)、InSitu Hybridization And Detection Systems（原位杂交和检测系统）、BioProbe、LabeledProbes（生物标记探针）、Signal Generating Systems（信号发生系统）。
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