Glycolysis Pathway
Glycolysis was one of the first metabolic pathways studied and is one of the best understood, in terms of the enzymes involved, their mechanisms of ac
A Method for Structure-5
ConclusionsQuorum-sensing signaling systems involving the interaction between a signaling peptide and its cognate histidine kinase receptor are widely
CXCR4 Signaling Pathway
CXCR4 is a chemokine receptor in the GPCR gene family, and is expressed by cells in the immune system and the central nervous system. In response to b
Oxidative reactions of the pentose phosphate pathway
One form of chemical energy used to drive biosynthetic reactions forward is the reducing power of the energy carrier NADPH. NADPH is essential to driv
Complement Pathway
The complement pathway consists of a series of over thirty proteins in plasma that are part of the immune response. Activation of the complement syste
PNAS：涂有骨生长因子的新型可植入工程骨
目前，麻省理工学院（MIT）的化学工程师们，设计了一种新型植入式组织支架，支架上涂有骨生长因子，可在几周时间内慢慢地被释放。当应用于骨损伤或缺陷时，这种涂层支架可诱导机体迅速形成外观和行为接近于原始组织的新骨。 与当前骨损伤的治疗标准相比，这种类型的涂层支架可提供显著的改善效果，当前的骨损伤治
699美元的癌症检测，你怎么看？
血液检测，在癌症早期检测领域越来越火，因省时省力，受到众多医学专业人士的青睐。近期也有研究表明血液检测可准确诊断肺癌，还可预测乳腺癌症的复发。如今不光是科研工作者热衷于挖掘血液检测在癌症早期检测中的潜力，企业对此也很感兴趣。美国圣地亚哥一家诊断公司Pathway Genomics在市场上销售6
MicroRNA Expression Profiling by Bead Array -1
MicroRNA Expression Profiling by Bead Array Technology in Human Tumor Cell Lines Treated with Interferon-Alpha-2aMicroRNAs are positive and negative r
699美元的癌症检测，你怎么看？
血液检测，在癌症早期检测领域越来越火，因省时省力，受到众多医学专业人士的青睐。近期也有研究表明血液检测可准确诊断肺癌，还可预测乳腺癌症的复发。如今不光是科研工作者热衷于挖掘血液检测在癌症早期检测中的潜力，企业对此也很感兴趣。美国圣地亚哥一家诊断公司Pathway Genomics在市场上销售69
绵羊血小板衍生生长因子酶联免疫分析
试剂盒使用说明书本试剂盒仅供研究使用。检测范围：使用目的：本试剂盒用于测定绵羊血清、血浆及相关液体样本中血小板衍生生长因子(PDGF)含量。实验原理：本试剂盒应用双抗体夹心法测定标本中绵羊血小板衍生生长因子 (PDGF)水平。用纯化的绵羊血小板衍生生长因子(PDGF)抗体包被微孔板，制成固相抗体，往
Omega Oxidation
NON-Clickable ImageWhile the main route of fatty acid metabolism is through beta-oxidation, some minor metabolic pathways such as omega oxidatio
Integrin Signaling Pathway
Integrins are cell surface receptors that interact with the extracellular matrix and mediate intracellular signals in response to the extracellular ma
Nature丨迟洪波组揭示代谢可以控制辅助性T细胞的可塑性
获得性免疫具有记忆效应。免疫系统在感染之后发展出的长期记忆T细胞可以应对未来感染。这些记忆T细胞具有干细胞性质。最近研究已经证实了在慢性感染中耗竭性CD8+ T细胞中，存在着一种独特的干细胞样的T细胞亚群【1】。然而，在慢性感染情况下，CD4+ T细胞是否也有类似性质的亚群仍不清楚。TH17细胞
Beta-Oxidation of Fatty Acids
Fatty acids provide highly efficient energy storage, storing much more energy for their weight than carbohydrates like glucose. Fatty acids are stored
SODD/TNFR1 Signaling Pathway
The tumor necrosis factor (TNF) receptor superfamily contains several members with homologous cytoplasmic domains known as death domains (DD). The int
许多动物细胞也能跟神经元一样伸长并彼此间形成突触...
新发现许多动物细胞也能跟神经元一样伸长并彼此间形成突触摘要：加州大学旧金山分校的研究人员发现，许多的动物细胞类型同样能够伸长并在彼此之间形成突触，它们采用信号蛋白代替神经元所利用的神经递质和电冲动作为信息单位。这一研究发现直接地挑战了普遍的动物细胞通讯生物学模型。相关文章发表于2014年1月2日的《
CD40L Signaling Pathway
The CD40 receptor was first associated with expression in B cells and the role it plays through its ligand CD40L (CD154) in moderating T cell activati
FAS signaling pathway ( CD95 )
Receptors in the TNF receptor family are associated with the induction of apoptosis, as well as inflammatory signaling. The Fas receptor (CD95) mediat
A Method for Structure-3
CSP-Dependent Transformation AssayTo determine if synthetic peptides activated quorum sensing for induction of genetic competence, we used theco
Bioactive Peptide Induced Signaling Pathway
Many different peptides act as signaling molecules, including the proinflammatory peptide bradykinin, the protease enzyme thrombin, and the blood pres
Toll-Like Receptor Pathway
The innate immune response responds in a general manner to factors present in invading pathogens. Bacterial factors such as lipopolysaccharides (LPS,
Classical Complement Pathway
The complement system is part of the defense against invading cells and is composed of about twenty different proteins found in the plasma. When activ
Lissencephaly gene (LIS1) in neuronal migration and development
Integration of pathways that regulate nucleokinesis during neuronal migration and a model of LIS1 mediating CLIP-170 interactions with the dynein/dyna
Comparison of Beta oxidation in mitochondria and peroxisomes andglyoxysomes
In addition to the beta-oxidation of fatty acids in mitochondria, animal cells carry out beta-oxidation in another organelle, the peroxisome. Although
Rac 1 cell motility signaling pathway
Rac-1 is a small G-protein in the Rho family that regulates cell motility in response to extracellular signals. Several changes in cytoskeletal struct
Pathway Genomics付款4百万美元用于回扣指控
分析测试百科网讯 政府机构近日宣布，Pathway Genomics已同意支付约4百万美元用于解决美国司法部的指控，指控其向医生和医生组织非法支付回扣以交换转诊病人。 美国律师Laura Duffy在声明中说道：“给医疗服务提供者回扣用于换取病人的转诊削弱医师的医疗判断，并且利用了患者的信任。
Bone Remodelling
Bone density and structure is maintained through a balance of bone resorption by osteoclasts and bone deposition by osteoblasts. The combination of si
Biosynthesis of Tryptophan in Bacteria and Plants
The aromatic amino acid tryptophan is an essential nutrient, meaning that humans and animals do not themselves have the biosynthetic machinery to synt
Joint formation in chick limb bud CAM grafts
AbstractChoriallantoic membrane (CAM) limb grafting functions as a method to isolate the inductive eve
周界文/吴皓/陈枢青合作组发现死亡受体DR5信号传递机制
TNFR超家族（Tumor Necrosis Factor receptor superfamily, TNFRSF）在细胞凋亡和炎症等过程中发挥重要作用，同时也参与细胞增殖和细胞分化。大部分TNFRSF成员分布于免疫细胞，负责调控免疫细胞活性，比如4-1BB (CD137)、OX40、BCMA
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