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Abnova/BCOR Split FISH Probe/1kit/FS0063

价格
面议
货号:FS0063
浏览量:127
品牌:Abnova
服务
全国联保
正品保证
正规发票
签订合同
商品描述
  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene split using Fluoresecent In Situ Hybridization Technique. (Technology)
  • Form:
  • Liquid
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.QC Testing of FS0063
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • Hybridization position of the probes on the chromosome.
  • Probe 1:Size:Fluorophore:Location:
  • BCORApproximately 350kb TexRedXp11.4
  • Probe 2:Size:Fluorophore:Location:
  • BCORApproximately 430kb FITCXp11.4
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Datasheet:
  • PDF DownloadDownload
  • Publication Reference
  • 1.
  • A Case Series of BCOR Sarcomas With a New Splice Variant of BCOR/CCNB3 Fusion Gene.Anastasios Kyriazoglou, Natalia Tourkantoni, Michalis Liontos, Flora Zagouri, Louisa Mahaira, Alexandra Papakosta, Dimitra Michali, Amalia Patereli, Kalliopi Stefanaki, Vasiliki Tzotzola, Evangelia Skoura, Margarita Baka, Sofia Polychronopoulou, Antonis Kattamis, Efthymios Dimitriadis.In Vivo. Sep-Oct 2020;34(5):2947-2954. doi: 10.21873/invivo.12125.
  • Applications
  • Fluorescent In Situ Hybridization (Cell)
  • PDF DownloadProtocol Download
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Gene Information
  • Entrez GeneID:
  • 54880
  • Gene Name:
  • BCOR
  • Gene Alias:
  • ANOP2,FLJ20285,FLJ38041,KIAA1575,MAA2,MCOPS2,MGC131961,MGC71031
  • Gene Description:
  • BCL6 co-repressor
  • Omim ID:
  • 300166, 300485
  • Gene Ontology:
  • Hyperlink
  • Gene Summary:
  • The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • 5830466J11Rik,8430401K06Rik,BCL-6 interacting corepressor,OTTHUMP00000025766,OTTHUMP00000025768
Abnova的Abnova Diagnostics F蛋白表达系统基于小麦胚芽的真核翻译设备。小麦胚在浓缩干燥状态下储存所有翻译成分,一旦发芽就准备好进行蛋白质合成。常规的小麦胚芽提取物包含RNA N-糖苷酶三丁酸酯和其他翻译抑制剂,例如硫蛋白,核糖核酸酶,脱氧核糖核酸酶和蛋白酶。这些抑制剂来自胚乳。大量洗涤小麦胚芽以消除胚乳污染物已导致提取物具有高度的稳定性和活性。通过将具有5'cap和多(RSA)尾巴的mRNA与该提取物与专有脂质体结合使用,进行体外翻译反应产生足够量的膜蛋白,该膜蛋白被脂质体捕获,导致正确的构象和生物学功能必不可少的折叠。该系统相对于普遍使用的蛋白质表达平台(例如大肠杆菌,昆虫细胞和哺乳动物细胞)具有明显优势,这些平台都是体内系统,并且在细胞膜的约束下导致产量和稳定性低。此外,体外小麦胚芽系统适于自动化以用于高通量小分子以及生物学筛选和表征。