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Abnova/AHR (Human) Cell-Based ELISA Kit/1kit/KA2562

价格
面议
货号:KA2562
浏览量:127
品牌:Abnova
服务
全国联保
正品保证
正规发票
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商品描述
  • Specification
  • Product Description:
  • AHR (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of AHR expression in cultured cells.
  • Reactivity:
  • Human, Mouse, Rat
  • Storage Instruction:
  • Store the kit at 4°C.
  • Protocol:
  • PDF DownloadProtocol Download
  • Suitable Sample:
  • Attached Cell, Loosely Attached Cell, Suspension Cell
  • Label:
  • HRP-conjugated
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Datasheet:
  • PDF DownloadDownload
  • Applications
  • Qualitative
  • Application Image
  • Qualitative
  • AHR
  • AHRR
  • Gene Information
  • Entrez GeneID:
  • 196
  • Protein Accession#:
  • P35869 (Gene ID : 196);A9YTQ3 (Gene ID : 57491)
  • Gene Name:
  • AHR
  • Gene Alias:
  • bHLHe76
  • Gene Description:
  • aryl hydrocarbon receptor
  • Omim ID:
  • 600253
  • Gene Ontology:
  • Hyperlink
  • Gene Summary:
  • This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons. [provided by RefSeq
  • Other Designations:
  • AH-receptor,aromatic hydrocarbon receptor
  • Gene Information
  • Entrez GeneID:
  • 57491
  • Protein Accession#:
  • P35869 (Gene ID : 196);A9YTQ3 (Gene ID : 57491)
  • Gene Name:
  • AHRR
  • Gene Alias:
  • AHH,AHHR,KIAA1234,MGC167813,MGC176630,bHLHe77
  • Gene Description:
  • aryl-hydrocarbon receptor repressor
  • Omim ID:
  • 606517
  • Gene Ontology:
  • Hyperlink
  • Gene Summary:
  • Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor"s binding partner, arylhydrocarbon receptor nuclear translocator. The protein encoded by this gene represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, the encoded protein can bind to nuclear factor kappa-B. [provided by RefSeq
  • Other Designations:
  • aryl hydrocarbon hydroxylase regulator,aryl hydrocarbon receptor regulator,arylhydrocarbon receptor repressor,dioxin receptor repressor
Abnova的Abnova Diagnostics F蛋白表达系统基于小麦胚芽的真核翻译设备。小麦胚在浓缩干燥状态下储存所有翻译成分,一旦发芽就准备好进行蛋白质合成。常规的小麦胚芽提取物包含RNA N-糖苷酶三丁酸酯和其他翻译抑制剂,例如硫蛋白,核糖核酸酶,脱氧核糖核酸酶和蛋白酶。这些抑制剂来自胚乳。大量洗涤小麦胚芽以消除胚乳污染物已导致提取物具有高度的稳定性和活性。通过将具有5'cap和多(RSA)尾巴的mRNA与该提取物与专有脂质体结合使用,进行体外翻译反应产生足够量的膜蛋白,该膜蛋白被脂质体捕获,导致正确的构象和生物学功能必不可少的折叠。该系统相对于普遍使用的蛋白质表达平台(例如大肠杆菌,昆虫细胞和哺乳动物细胞)具有明显优势,这些平台都是体内系统,并且在细胞膜的约束下导致产量和稳定性低。此外,体外小麦胚芽系统适于自动化以用于高通量小分子以及生物学筛选和表征。