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联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
- Specification
- Product Description:
- ACACA (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of ACACA expression in cultured cells.
- Reactivity:
- Human, Mouse, Rat
- Storage Instruction:
- Store the kit at 4°C.
- Protocol:
Protocol Download
- Suitable Sample:
- Attached Cell, Loosely Attached Cell, Suspension Cell
- Label:
- HRP-conjugated
- Detection Method:
- Colorimetric
- Regulation Status:
- For research use only (RUO)
- Datasheet:
- Download
- Applications
- Qualitative
- Application Image
- Qualitative
- Gene Information
- Entrez GeneID:
- 31
- Protein Accession#:
- Q13085
- Gene Name:
- ACACA
- Gene Alias:
- ACAC,ACC,ACC1,ACCA
- Gene Description:
- acetyl-Coenzyme A carboxylase alpha
- Omim ID:
- 200350
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5" sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- ACC-alpha,OTTHUMP00000164069,acetyl-CoA carboxylase 1,acetyl-CoA carboxylase-alpha
- Gene Pathway
- Fatty acid biosynthesis
- Insulin signaling pathway
- Metabolic pathways
- Propanoate metabolism
- Pyruvate metabolism
- Related Disease
- Breast cancer
- Breast Neoplasms
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Drug Toxicity
- Edema
- Genetic Predisposition to Disease
- Hypercholesterolemia
- Hyperlipidemias
- Hypertriglyceridemia
- Obesity
- Ovarian cancer
- Psychotic Disorders
- Tobacco Use Disorder
