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联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
- Specification
- Product Description:
- ACLY (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of ACLY expression in cultured cells.
- Reactivity:
- Human, Mouse, Rat
- Storage Instruction:
- Store the kit at 4°C.
- Protocol:
Protocol Download
- Suitable Sample:
- Attached Cell, Loosely Attached Cell, Suspension Cell
- Label:
- HRP-conjugated
- Detection Method:
- Colorimetric
- Regulation Status:
- For research use only (RUO)
- Datasheet:
- Download
- Applications
- Qualitative
- Application Image
- Qualitative
- Gene Information
- Entrez GeneID:
- 47
- Protein Accession#:
- P53396
- Gene Name:
- ACLY
- Gene Alias:
- ACL,ATPCL,CLATP
- Gene Description:
- ATP citrate lyase
- Omim ID:
- 108728
- Gene Ontology:
- Hyperlink
- Gene Summary:
- ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000164773
- Gene Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Citrate cycle (TCA cycle)
- Metabolic pathways
- Reductive carboxylate cycle (CO2 fixation)
- Related Disease
- Schizophrenia
- Schizophrenia
- Weight Gain
