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商品描述
IRF4 Antibody
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Product Description | IRF4 is a transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. |
Species | Rabbit |
Formulation | 250 µg/mL in 0.1 N Tris-acetate, pH7.0, 0.01% NaN3, and 50%glycerol |
Storage & Stability | Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if properly stored. |
Immunogen | Human IRF4 peptide-KLH conjugates |
Purification | The antibody was affinity purified with Human IRF4 peptide on Agarose. |
Applications | ELISA,WB, IP. |
Specificity | The antibody recognizes IRF4 at around 50 kd. |
Scientific Description | IRF4 also called lymphocyte-specific interferon regulatory factor. It binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. |
Product Specific References | 1.Biochem. J. 1989.257: 535-540. |