5-SIMA phosphoramidite Catalogue number: 303-57Purity: > 95%Formula: C58H64Cl2N3O10PMolecular Weight: 1065.0Diluent: Anhydrous AcetonitrileCoupling: No changes needed from standard method recommended by synthesizer manufacturerDeprotection: No changes needed from standard method recommended by synthesizer manufacturer.SIMA labeled oligos are stable at 55°C in ammonium hydroxide (up to 6-8 hours) and canbe deprotected with AMA.Storage: Freezer storage, -10 to -30°C, dry.Stability in Solution: 2-3 days, <90% efficient after 4 daysPrice and Ordering Information

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metkinen chemistry嘌呤3'-氨基-3'-脱氧核苷通过生物转化合成3'-氨基-3'脱氧核苷，并用作制备相应的3'-氨基-3'-脱氧核苷-5'-CE亚磷酰胺的起始化合物。后者是组装RNA寡核苷酸N3'-> P5'氨基磷酸酯的基础。