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蚂蚁淘在线 / 品牌中心 / indoor biotechnologies / indoor biotechnologies/Recombinant Alt a 1 (RP-AA1-1)/1/RP-AA1-1
商品描述
| Allergen: | rAlt a 1 (Alternaria alternata allergen 1) |
| Unit: | 250µg |
| Source: | Pichia pastoris |
| Mol. Wt: | ~15kD |
| Purification: | Purified from Pichia pastoris culture by HPLC gel filtration. Purity >95% by SDS-PAGE. |
| Concentration: | See product insert. |
| Formulation: | Preservative-free and carrier-free in phosphatebuffered saline, pH 7.4. Filtered through 0.22µm filter. |
| Storage: | Store at -20ºC. |
| Notes: | 1) rAlt a 1 produced in Pichia pastoris has been observed as a dimer at ~30kD in the SDS-PAGE gel. |
| Genbank: | |
| PDB: | |
| Product Resources: | Recombinant Alt a 1 Certificate of Analysis Focus on... Alt a 1 |
| Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. | |
| References: | |
| Chruszcz M, Chapman MD, Osinski T, Solberg R, Demas M, Porebski PJ, Majorek KA, Pomés A, Minor W. Alternaria alternata allergen Alt a 1: A unique β-barrel protein dimer found exclusively in fungi. J Allergy Clin Immunol. 2012 Jul;130:241-7. | |
| Vailes L, Sridhara S, Cromwell O, Weber B, Breitenbach M, Chapman M. Quantitation of the major fungal allergens, Alt a 1 and Asp f 1, in commercial allergenic products. J Allergy Clin Immunol. 2001;107:641-6. | |
| Vailes LD, Perzanowski MS, Wheatley LM, Platts-Mills TA, Chapman MD. IgE and IgG antibody responses to recombinant Alt a 1 as a marker of sensitization to Alternaria in asthma and atopic dermatitis. Clin Exp Allergy. 2001;31:1891-5 | |
