Allergen:	rAlt a 1 (Alternaria alternata allergen 1)
Unit:	250µg
Source:	Pichia pastoris
Mol. Wt:	~15kD
Purification:	Purified from Pichia pastoris culture by HPLC gel filtration. Purity >95% by SDS-PAGE.
Concentration:	See product insert.
Formulation:	Preservative-free and carrier-free in phosphatebuffered saline, pH 7.4. Filtered through 0.22µm filter.
Storage:	Store at -20ºC.
Notes:	1) rAlt a 1 produced in Pichia pastoris has been observed as a dimer at ~30kD in the SDS-PAGE gel.
Genbank:
PDB:
Product Resources:	Recombinant Alt a 1 Certificate of Analysis Focus on... Alt a 1
Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use.
References:
Chruszcz M, Chapman MD, Osinski T, Solberg R, Demas M, Porebski PJ, Majorek KA, Pomés A, Minor W. Alternaria alternata allergen Alt a 1: A unique β-barrel protein dimer found exclusively in fungi. J Allergy Clin Immunol. 2012 Jul;130:241-7.
Vailes L, Sridhara S, Cromwell O, Weber B, Breitenbach M, Chapman M. Quantitation of the major fungal allergens, Alt a 1 and Asp f 1, in commercial allergenic products. J Allergy Clin Immunol. 2001;107:641-6.
Vailes LD, Perzanowski MS, Wheatley LM, Platts-Mills TA, Chapman MD. IgE and IgG antibody responses to recombinant Alt a 1 as a marker of sensitization to Alternaria in asthma and atopic dermatitis. Clin Exp Allergy. 2001;31:1891-5

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