Mag-Fura-2 is a UV-excitable fluorescent indicator for magnesium with a Kd of 1.9 mM (1,2).

Mag-Fura-2 is a UV-excitable fluorescent indicator for magnesium with a K_d of 1.9 mM (1,2). Similar to Fura-2, the excitation wavelength of Mag-Fura-2 undergoes a blue shift from 369 nm to 330 nm. Mag-Fura-2 also responds to Ca² but with a significantly lower K_d than Fura-2 for Ca² . An important application of Mag-Fura-2 is its use in detecting high, transient Ca² concentration during Ca² spikes (3,4). Mag-Fura-2/tetraammonium salt can be loaded into cells by microinjection or scrape loading. Also see Mag-Fura-2, tetrasodium salt (50036) and the cell membrane-permeant Mag-Fura-2 AM ester (50037, 50038, 50039).

• Light yellow solid soluble in water (pH > 6)
• Store at -20°C and protect from light
• C₁₈H₁₀K₄N₂O₁₁
• MW: 587
• [132319-57-4]

References

1. PNAS 86, 2981 (1989).

2. Am J Physiol 256, C540 (1989).

3. Neuron 10, 21 (1993).

4. Biophys J 68, 2156 (1995).

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