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OZ Biosciences/ViroMag R/L/ViroMag R/L Starting Kit/KC30700

价格
¥1078000.00
货号:KC30700
浏览量:127
品牌:OZ Biosciences
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商品描述

ViroMag R/L Transduction Reagent is a magnetic nanoparticles formulation optimized for Retroviruses and Lentiviruses. Based on the Magnetofection™ technology, this reagent allows concentrating the complete applied dose of Retro/Lentiviral particles onto cells within minutes, inducing a significant improvement of virus infectivity with extremely low vector doses. Due to its specific properties, ViroMag R/L is ideal to infect non permissive cells. This reagent demonstrates an exceptionally high efficiency to promote, control and assist viral transductions in a  so that no molecular biology processes or biochemical modifications are required.

 
  • Increase transduction efficiency

  • Accelerate the transduction process

  • Efficient for hard-to-infect and non-permissive cells

  • Concentrate the viral dose onto the cells

  • Suitable for all type of Retro/Lentivirus

  • Synchronise cells adsorption/infection without modifications of the viruses

 

"Use of R/L to knock down a gene by CRISPR/Cas9-guided genome editing with Lentivirus in THP-1 cells" Safronova A et al, Nature Immuno. 2018
"The magnetofection beads have been a game-changer for the transduction efficiency of our lentiviruses. We are using very hard to transduce B-lymphoblastomas that grow in suspension and viral concentration using filtering in conjunction with ViroMag R/L has brought our efficiency up from about 2% to 70-80%. High transduction efficiency on mammary epithelial organoids in suspension"
Erna Magnúsdóttir - University of Iceland
 
 
 

ViroMag R/L transduction reagent:

Sizes:

  • 100 µL 30-500 transductions in 96-well plate

  • 200 µL 60-1,000 transductions in 96 well plate

  • 1 mL 300-5,000 transductions in 96-well plate

  • #KC30700: ViroMag R/L Starting Kit with Super Magnetic plate + 200µL of ViroMag R/L

 

Storage: +4°C

Shipping Conditions: Room Temperature

 

  • This reagent needs to be used with a magnetic plate

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OZ Biosciences的VaxOZ佐剂非常适合作为金标准参照物和任何免疫实验。也可以使用您自己的免疫刺激剂来定制它们。当前,佐剂仍然是提高常规和下一代疫苗效率的最重要策略。遗传佐剂是与特定抗原结合使用的免疫学试剂,可增强免疫反应。直接后果是与仅使用抗原相比,会产生更多的抗体和更长的免疫力,从而使疫苗所需的抗原剂量降至最低。特别是,基于DOTAP(1,2-油酰基--3-三甲基铵-丙烷)的阳离子脂质可诱导树突状细胞成熟,然后运输至引流淋巴结以激活抗原特异性T细胞。疫苗佐剂OZ生物科学VaxOZ佐剂是体内制造和质量控制的产品,仅用于研究目的。- AlumVax氢氧化物 / 磷酸盐,两个古典铝基佐剂- IFAVax, 不完全弗氏佐剂- CFAVax,完全弗氏佐剂- SqualVax,一个纳米油包水乳液-  CaLiVax-DOTAP, 对于脂质体介导的DNA或蛋白质疫苗基于阳离子脂质的组合物。