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商品描述
BIOLOGICAL INFORMATION
DescriptionC-type natriuretic peptide is produced in the hypothalamus, anterior pituitary, and most major endocrine glands. C-type natriuretic peptide has potent venodilatory and coronary vasodilatory effects, but minimal effects on renal function.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10556
CAS No.127869-51-6
NameC-Type Natriuretic Peptide (CNP) (1-22), human
Chemical NameC-Type-Natriuretic-Peptide-(CNP)-(1-22),-human
Purity≥98%
SynonymsCNP (1-22)； humanCNP
FormulaC93H157N27O28S3
Molecular Weight2197.6
One Letter CodeGLSKGCFGLKLDRIGSMSGLGC
Three Letter CodeGLY-LEU-SER-LYS-GLY-CYS-PHE-GLY-LEU-LYS-LEU-ASP-ARG-ILE-GLY-SER-MET-SER-GLY-LEU-GLY-CYS
SMILESCCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)CC(C)C)CCCCN)CC(C)C)CC2=CC=CC=C2)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)CN)C(=O)O)CC(C)C)CO)CCSC)CO
InChI KeyUHSBKBYWHCBDCJ-DYGWFTAGSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1.Burley DS, Cox CD, Zhang J, et al. Natriuretic peptides modulate ATP-sensitive K(+) channels in rat ventricular cardiomyocytes. Basic Res Cardiol. 2014 Mar;109(2):402. PMID: 24477916.
2.Azer J, Hua R, Krishnaswamy PS, et al. Effects of natriuretic peptides on electrical conduction in the sinoatrial node and atrial myocardium of the heart. J Physiol. 2014 Mar 1;592(Pt 5):1025-45. PMID: 24344164.
3.De Jonge HR, Tilly BC, Hogema BM, et al. cGMP inhibition of type 3 phosphodiesterase is the major mechanism by which C-type natriuretic peptide activates CFTR in the shark rectal gland. Am J Physiol Cell Physiol. 2014 Feb;306(4):C343-53. PMID: 24259420.
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
