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商品描述
BIOLOGICAL INFORMATION
DescriptionPrRP is a member of the structurally related RF-amide family and it has been found in the medulla oblongata, hypothalamus and pituitary. PrRP can cause increases in intracellular calcium and activation of c-Jun N-terminal protein kinase (JNK) in a pertussis toxin insensitive manner; PrRP agonist that stimulates the release of prolactin from the anterior pituitary.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10772
CAS No.235433-36-0
NameProlactin Releasing Peptide (12-31), human
Chemical NameProlactin-Releasing-Peptide-(12-31),-human
Purity≥98%
SynonymsN/A
FormulaC104H158N32O26
Molecular Weight2272.6
One Letter CodeTPDINPAWYASRGIRPVGRF-NH2
Three Letter CodeTHR-PRO-ASP-ILE-ASN-PRO-ALA-TRP-TYR-ALA-SER-ARG-GLY-ILE-ARG-PRO-VAL-GLY-ARG-PHE-NH2
SMILESCCC(C)C(C(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)NC(CC2=CC=CC=C2)C(=O)N)NC(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(C)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(CC4=CNC5=CC=CC=C54)NC(=O)C(C)NC(=O)C6CCCN6C(=O)C(CC(=O)N)NC(=O)C(C(C)CC)NC(=O)C(CC(=O)O)NC(=O)C7CCCN7C(=O)C(C(C)O)N
InChI KeyCPYRNXJVNKJULS-FWGIIJIJSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1.Laurent P, et al. The prolactin-releasing peptide antagonizes the opioid system through its receptor GPR10. Nat. Neurosci. Dec 2005; 8(12): 1735-1741.
2.Romero A., etc. Prolactin-releasing peptide is a potent mediator of the innate immune response in leukocytes from Salmo salar. Vet Immunol Immunopathol. 2012 Jun;147(3-4):170 - 9.
3.Mera T, et al. Prolactin-releasing peptide is a potent mediator of stress responses in the brain through the hypothalamic paraventricular nucleus. Neuroscience. May 2006; Epub ahead of print.
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
