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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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商品描述
BIOLOGICAL INFORMATION
DescriptionThis insulin B-chain peptide binds to a class II histocompatibility complex (MHC) allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic ß cells leading to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to autoantibodies and insulitis.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10749
CAS No.N/A
NameInsB 9-23
Chemical NameInsB-9-23
Purity≥98%
SynonymsN/A
FormulaN/A
Molecular Weight1645.9
One Letter CodeSHLVEALYLVCGERG
Three Letter CodeSer-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly
SMILESN/A
InChI KeyN/A
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
Stability≥ 2 years
REFERENCES & CITATIONS
1.Devendra, D. et al. Diabetes 54, 2549 (2005)
2.Starwalt, S. et al. Protein Eng. 16, 147 (2003)
3.Lee, L. et al. PNAS 102, 15995 (2005)
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
