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商品描述
BIOLOGICAL INFORMATION
DescriptionAlpha-MSH (alpha melanocyte-stimulating hormone) is an ancient tridecapeptide with potent inhibitory activity in all major forms of inflammation. ACTH has structural similarities to alpha-MSH. ACTH and alpha-MSH can induce grooming, stretching, yawning, penile erection responses in male rats, site of action in the brain and role of melanocortin receptors.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10543
CAS No.581-05-5
Nameα-Melanocyte-Stimulating Hormone (MSH), amide
Chemical Nameα-Melanocyte-Stimulating-Hormone-(MSH),-amide
Purity≥98%
SynonymsN/A
FormulaC77H109N21O19S
Molecular Weight1664.9
One Letter CodeAc-SYSMEHFRWGKPV-NH2
Three Letter CodeAc-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-NH2
SMILESCC(C)C(C(=O)N)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CNC=N5)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CO)NC(=O)C
InChI KeyWHNFPRLDDSXQCL-UAZQEYIDSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1.Jo H, et al. Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of α-MSH-stimulated melanogenesis. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3374-3377.
2.Lu XY, et al. Interaction between alpha-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses. J Neurosci. 2003 Aug 27;23(21):7863-72.
3.Yamaoka-Tojo M, et al. Central neurotranspeptide, alpha-melanocyte-stimulating hormone (alpha-MSH) is upregulated in patients with congestive heart failure. Intern. Med. Jul 2006; 45(7): 429-434.
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
