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商品描述
BIOLOGICAL INFORMATION
DescriptionNeurokinin B belongs to the tachykinin family. Neurokinin B may play an important role in the olfactory, gustatory, visceral, and neuroendocrine processing information. Neurokinin B is potent bronchioconstrictor and has neruomodulatory roles in various brain functions. Neurokinin B is a member of the tachykinin family of neuropeptides that also includes Substance P and Neurokinin A. These carboxyl terminal-amidated peptides are derived from two preprotachykinin genes - the PPT-A gene encodes the sequences of Substance P, Neurokinin A, and neuropeptide K and the PPT-B gene encodes the sequence of Neurokinin B. Neurokinin B stimulate the production of immunoglobulins in peripheral B lymphocytes, This conditional response to Neurokinin B is likely due NK-3 receptors present only following co-culture and activation.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10562
CAS No.86933-75-7
NameNeurokinin B
Chemical NameNeurokinin-B
Purity≥98%
SynonymsNKB
FormulaC55H79N13O14S2
Molecular Weight1210.42
One Letter CodeDMHDFFVGLM-NH2
Three Letter CodeASP-MET-HIS-ASP-PHE-PHE-VAL-GLY-LEU-MET-NH2
SMILESCC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(=O)O)NC(=O)C(CC3=CN=CN3)NC(=O)C(CCSC)NC(=O)C(CC(=O)O)N
InChI KeyNHXYSAFTNPANFK-YXADSUOLSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1.Cuadrado I, et al. Mapping of neurokinin b in the cat brainstem. Anat. Embryol. (Berl). Sep 2005; 210(2): 133-143.
2.Duarte CR, et al. Incongruent pattern of neurokinin B expression in rat and mouse brains. Cell Tissue Res. Jan 2006; 323(1): 43-51.
3.Krajewski SJ, et al. Morphologic evidence that neurokinin B modulates gonadotropin-releasing hormone secretion via neurokinin 3 receptors in the rat median eminence. J. Comp. Neurol. Aug 2005; 489(3): 372-386.
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS