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蚂蚁淘在线 / 品牌中心 / Ontores / Ontores/Cyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH)sulfoxide/25mg/ONP10941
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商品描述
BIOLOGICAL INFORMATION
DescriptionThis sulfur-bridged cyclic RGD peptide is a potent inhibitor of the binding of glycoprotein IIb/IIIa to fibrinogen with an IC₅₀ of 1.5 nM. Furthermore, it is a highly potent inhibitor of fibrinogen-mediated platelet aggregation (IC₅₀ = 0.15 µM). Its antithrombotic activity in vivo may render this compound useful in the treatment of arterial thromboembolic diseases.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10941
CAS No.143120-27-8
NameCyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH)sulfoxide
Chemical NameCyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH)sulfoxide
Purity≥98%
SynonymsN/A
FormulaC26H36N8O11S
Molecular Weight668.68
One Letter CodeN/A
Three Letter CodeCyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH)sulfoxide
SMILESC1C(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)CS1=O)CC2=CC=C(C=C2)O)CCCN=C(N)N)CC(=O)O)C(=O)O
InChI KeyDMXRDQJVBMEHPP-OREKCURGSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
Stability≥ 2 years
REFERENCES & CITATIONS
1.P.L.Barker et al., J. Med. Chem., 35, 2040 (1992)
2.Y.Imura et al., Blood, 80, 1247 (1992)
3.H.R.Lu et al., Thromb. Haemost., 67, 686 (1992)
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
