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商品描述
20S Proteasome (human) (untagged)
Product Code:
SBB-PP0005-C050
Pack Size:
50 ug
Form:
Protein
Shipping Temp:
Dry Ice
Storage Temp:
-80C
Dry Ice:
This product requires shipping in dry ice and an additional shipping charge will be made.
Target Species:
Human
Product Type:
Recombinant Proteins
Description:
Protein. Human 20S Proteasome. Source: Human Erythrocytes. Formulation: Liquid. In 50mM HEPES pH 7.6, 100mM sodium chloride, 1mM DTT. Purity: >95% (SDS-PAGE). The ubiquitin-proteasome pathway is the major proteolytic system in eukaryotic cells, where it catalyzes the selective degradation of short-lived regulatory proteins or the rapid turnover of misfolded proteins. One of the most important proteases in this pathway is the 26S proteasome, an ATP-dependent proteolytic complex, which is formed by the association of the barrel-shaped 20S proteasome (700kDa) and two 19S (700kDa) regulatory complexes. The 20S catalytic core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha-subunits and 2 rings are composed of 7 beta-subunits. The 20S catalytic core is able to degrade a variety of peptide substrates and poly-ubiquitinated proteins involved with apoptosis, DNA repair, endocytosis and cell cycle control.
Supplier:
South Bay Bio
Product Category:
Ubiquitin > Ubiquitin Proteins
Product Line Areas: Protein, Cancer, Inflammation, Neurodegenerative Disease, Ubiquitin Pathway
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- Further Information
Product Code:
SBB-PP0005-C050 Price (50 ug):
£154.00 excluding VATPrice (CI_Pack1): Please enquire
Quantity: Add to basket
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