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蚂蚁淘在线 / 品牌中心 / Bio-Synthesis / Bio-Synthesis/Beta - Amyloid (11 - 42), FAM - labeled/0.1 mg/13805-001
商品描述
Beta - Amyloid (11 - 42), FAM - labeled
Sequence (1LC):
5-FAM-EVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Sequence (3LC):
5 - FAM - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - COOH
Catalog :
13805-001
Unit:
0.1 mg
Price/Unit:
$281(For other quantities please Contact Us or call 972-420-8505)
Purity:
Purity > 95% by HPLC
Format:
Each vial contains lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt
Description:
This is amino acids 11 to 42 fragment of beta-amyloid peptide labeled with 5-FAM (Abs/Em=492/518 nm). Post-mortem Alzheimer’s diseased (AD ) brain specimens reveal significant levels of this b-amyloid peptide within insoluble amyloid pools. Beta-secretase enzyme or beta-amyloid precursor protein-cleaving enzyme (BACE) generates the N terminus of b-amyloid, ultimately leading to the production of full-length beta-amyloid (1-40/42) or truncated beta-amyloid (11-40/42). The abundance of b-amyloid (11-40/42) produced by BACE suggests that their roles in AD pathogenesis may be important.
Storage:
Store the peptide at -20°C. Keep container tightly
Product Usage:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
M.W.:
3694.2 g/mol
Reference/Citations:
- Huse, J. T. et al. J. Biol. Chem. 277, 16278 (2002);
- Qahwash, I. et al. J. Biol. Chem. 279, 39010 (2004);
- Liu, K. et al. Biochem. 41, 3128 (2002).
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