Product information "Rapamycin"
Isolated from Streptomyces hygroscopicus. Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the molecular target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an alternative to calcineurin inhibitors. Restricts the proliferation of smooth-muscle cells by blocking cell cycle progression at the G1/S transition. Anti-proliferative. Antitumor compound. Apoptosis enhancer. Activator of autophagy both in vitro and in vivo. Anti-HIV and anti-aging compound. Neuroprotective.
Keywords: | Sirolimus, Rapamune, NSC 226080, Antibiotic AY-22989, WY-090217, RAPA, SILA 9268A, CCRIS 9024 |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-CN2-0025-M001 |
Properties
Application: | MTOR inhibitor, Immunsuppressant, Apoptosis inducer |
MW: | 914,2 D |
Formula: | C51H79NO13 |
Purity: | >98% |
Format: | Solid |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution Our products are for laboratory research use only: Not for administration to humans!
美国生物学(USBiologic)位于美国马萨诸塞州的Swampscott。它的生产能力包括抗生素,抗体,琼脂糖,白蛋白,氨基酸,生化试剂,生物制剂,细胞因子,酶,培养基,分子生物学试剂盒,肽和血清。所有产品均提供经过认证的测试结果。USBio提供了多种抗体。