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蚂蚁淘在线 / 品牌中心 / Biomol / Biomol/Citrullinated Histone H3 (Clone 11D3) ELISA Kit/96 wells/Cay501620-96
商品描述
Product information "Citrullinated Histone H3 (Clone 11D3) ELISA Kit"
Histone H3 is citrullinated by peptidylarginine deiminase 4 (PAD4) at residues R2, R8, and R17 during the processes of epigenetic chromatin remodeling and neutrophil extracellular trap (NET) formation. In vitro, citrullinated H3 (CitH3) is released from neutrophils that have been stimulated with calcium ionophore during the process of NETosis, and can be freed from NETs by treatment with nuclease. The measurement of CitH3, either in cell lysates or released during NETosis can be used as a functional readout of pharmacological PAD inhibition.
| Keywords: | CitH3 (Clone 11D3) EIA Kit |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 501620-96 |
Properties
| Application: | ELISA |
| Clone: | 11D3 |
| Format: | Solid Phase |
Database Information
| KEGG ID : | K11253 | Find alternatives |
| UniProt ID : | P68431 | Find alternatives |
| Gene ID | GeneID 8350 | Find alternatives |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |  |
| H Phrases: | H315 |
| P Phrases: | P264, P280, P321, P302+P352, P332+P313, P362+P364 |
Caution Our products are for laboratory research use only: Not for administration to humans!
