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商品描述
Product information "Indomethacin"
Indomethacin is a non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and COX-2, respectively). It reduces filter paper-disc induced growth of granulation tissue, a marker of inflammation, in chick chorioallantoic membranes. Indomethacin reduces ocular inflammation induced by bovine serum in rabbits. It also reduces paw edema in a rat model of carrageenan-induced inflammation.
Keywords: | Indocin, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid |
Supplier: | Cayman Chemical |
Supplier-Nr: | 70270-1000 |
Properties
Application: | COX inhibitor |
MW: | 357.8 D |
Formula: | C19H16ClNO4 |
Purity: | >99% |
Format: | Crystalline Solid |
Database Information
CAS : | 53-86-1| Find alternatives |
KEGG ID : | K00509 | Find alternatives |
Handling & Safety
Storage: | +20°C |
Shipping: | +20°C (International: +20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: | |
H Phrases: | H300, H318, H335, H351, H360, H373, H413 |
P Phrases: | P201, P202, P260, P261, P264, P270, P271, P273, P280, P312, P314, P321, P330, P301+P310, P304+P340, P305+P351+P338, P308+P313, P405, P403+P233, P501 |
Caution Our products are for laboratory research use only: Not for administration to humans!