The evolutionarily conserved multifunctional polymerase-associated factor 1 (Paf1) complex (Paf1C), which is composed of at least five subunits (Paf1, Leo1, Ctr9, Cdc73, and Rtf1), plays vital roles in gene ...
Cdc48/p97 is an essential and highly conserved AAA+ ATPase that uses its protein-unfoldase activity to extract ubiquitinated polypeptides from macromolecular complexes and membranes. This motor has also been implicated in ...
Pex1 and Pex6 form a heterohexameric motor essential for peroxisome biogenesis and function, and mutations in these AAA-ATPases cause most peroxisome-biogenesis disorders in humans. The tail-anchored protein Pex15 recruits ...
B. cereus 23-40 10-8 30-25 >100 Salmonella sp - - >45 ...IC50 values (μg/ml) compoundsV-79 cellsKB cellsP388 cells D:A-friedo...sites, thus preventing topoisomerase-DNA cleavable complex formation [248]...
is modestly enriched by the Ub probe compared with the SUMO2 probe, ..., except for K27-linked di-Ub, which was purchased from UBPBio....coli. All dual promoter constructs contained a non-cleavable C-terminal...
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