英文名称| Rabbit EIF4G1 Polyclonal Antibody |
别名| EIF-4G1;EIF4F;EIF4G;EIF4GI;P220;PARK18 |
应用| WB,IHC,IF |
稀释比例| WB1:500-1:2000 IHC1:50-1:200 IF1:50-1:200 |
交叉反应| Human |
蛋白分子量| 175kDa |
Gene ID| 1981 |
保存| Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
储存液| PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法| Affinity purification |
亚型| IgG |
免疫原| A synthetic peptide of human EIF4G1 |
性状| Lyophilized or Liquid |
Swiss Prot| Q04637 |
克隆类型| Polyclonal Antibody |
来源| Rabbit |
背景资料| The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. |
