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DipraglurantmGluR5 antagonist |
Sample solution is provided at 25 µL, 10mM.
1. Sengmany K, Hellyer SD, et al. "Kinetic and system bias as drivers of metabotropic glutamate receptor 5 allosteric modulator pharmacology." Neuropharmacology. 2019 May 1;149:83-96.PMID:30763654
Quality Control & MSDS
- View current batch:
- Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure

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Cas No. | 872363-17-2 | SDF | Download SDF |
Synonyms | ADX 48621;ADX48621;ADX-48621 | ||
Chemical Name | 6-fluoro-2-(4-pyridin-2-ylbut-3-ynyl)imidazo[1,2-a]pyridine | ||
Canonical SMILES | C1=CC=NC(=C1)C#CCCC2=CN3C=C(C=CC3=N2)F | ||
Formula | C16H12FN3 | M.Wt | 265.29 |
Solubility | Soluble in DMSO | Storage | Store at -20°C |
Shipping Condition | Evaluation sample solution : ship with blue ice.All other available size:ship with RT , or blue ice upon request | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. |
Dipraglurant (ADX 48621) is mGlu5 receptor negative allosteric modulator.