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ApexBio/Tenofovir/10mM (in 1mL DMSO)/A5275

价格
¥3000.00
货号:A5275
浏览量:127
品牌:ApexBio
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商品描述
Related Products
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Molarity CalculatorDilution Calculator
TenofovirHIV reverse transcriptase inhibitor

Catalog No.A5275
SizePriceStockQty
10mM (in 1mL DMSO)
$55.00
In stock
25mg
$50.00
In stock
100mg
$150.00
In stock

Tel: +1-832-696-8203

Email: sales@apexbt.com

Worldwide Distributors

Sample solution is provided at 25 µL, 10mM.

Product Citations

1. Velichkovska M, Surnar B, et al. "Targeted Mitochondrial COQ(10) Delivery Attenuates Antiretroviral-Drug-Induced Senescence of Neural Progenitor Cells." Mol Pharm. 2019 Feb 4;16(2):724-736.PMID:30592424

Related Compound Libraries

  • DiscoveryProbe™ FDA-approved Drug Library
  • DiscoveryProbe™ Bioactive Compound Library
  • DiscoveryProbe™ Anti-infection Compound Library

Quality Control

Quality Control & MSDS

View current batch:
    Purity = 99.43%
  • COA (Certificate Of Analysis)
  • HPLC
  • NMR (Nuclear Magnetic Resonance)
  • MSDS (Material Safety Data Sheet)
  • Datasheet

Chemical structure

Tenofovir

Related Biological Data

Tenofovir

Tenofovir Dilution Calculator

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Tenofovir Molarity Calculator

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Chemical Properties

Cas No. 147127-20-6SDF Download SDF
Synonyms N/A
Chemical Name [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid
Canonical SMILES CC(CN1C=NC2=C1N=CN=C2N)OCP(=O)(O)O
Formula C9H14N5O4P M.Wt 287.21
Solubility ≥4.38mg/mL in DMSO with gentle warming Storage Store at -20°C
Physical AppearanceA solidShipping ConditionEvaluation sample solution : ship with blue ice.All other available size:ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

Selectively inhibits HIV reverse transcriptase (RNA-dependent DNA polymerase). Prevents cytotoxicity in SIV-infected C-8166 cells in vitro (IC50 = 1.5 μM). Antiviral agent.

ApexBio的3X FLAG Peptide FLAG标签系统利用与目标蛋白质1融合的短而亲水的8个氨基酸的肽段。FLAG肽与抗体M1结合。结合是钙依赖性方式2还是非依赖性3仍存在争议。该系统的缺点是单克隆抗体纯化基质不如其他基质稳定。通常,可以用特异性单克隆抗体检测小标签。为了改善对FLAG标签的检测,已经开发了3x FLAG系统。这种三级FLAG表位是亲水的,长22个氨基酸,可以检测到高达10 fmol的表达融合蛋白。激烈热球菌的带有FLAG标签的麦芽糖糊精结合蛋白已被结晶4,其晶体质量与未标记蛋白的晶体质量非常相似。 最后,可以通过用肠激酶处理去除FLAG标签,肠激酶对肽序列5的5个C末端氨基酸具有特异性。