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ApexBio/U-73122/10mM (in 1mL DMSO)/B3422

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¥3600.00
货号:B3422
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品牌:ApexBio
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U-73122inhibitor of phospholipase C, phospholipase A2, and 5-LO (5-lipoxygenase)

Catalog No.B3422
SizePriceStockQty
10mM (in 1mL DMSO)
$100.00
In stock
5mg
$64.00
In stock
10mg
$96.00
In stock
25mg
$180.00
In stock

Tel: +1-832-696-8203

Email: sales@apexbt.com

Worldwide Distributors

Sample solution is provided at 25 µL, 10mM.

Product Citations

1. Zhou J, Lai W, et al. "BLT1 in dendritic cells promotes Th1/Th17 differentiation and its deficiency ameliorates TNBS-induced colitis." Cell Mol Immunol. 2018 Apr 18.PMID:29670278

Related Compound Libraries

  • DiscoveryProbe™ Bioactive Compound Library
  • DiscoveryProbe™ Metabolism-related Compound Library

Quality Control

Quality Control & MSDS

View current batch:
    Purity = 98.05%
  • COA (Certificate Of Analysis)
  • HPLC
  • NMR (Nuclear Magnetic Resonance)
  • MSDS (Material Safety Data Sheet)

Chemical structure

U-73122

Related Biological Data

U-73122

U-73122 Dilution Calculator

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U-73122 Molarity Calculator

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Chemical Properties

Cas No. 112648-68-7SDF Download SDF
Synonyms N/A
Chemical Name 1-[6-[[(8R,9S,13S,14S,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]amino]hexyl]pyrrole-2,5-dione
Canonical SMILES CC12CCC3C(C1CCC2NCCCCCCN4C(=O)C=CC4=O)CCC5=C3C=CC(=C5)OC
Formula C29H40N2O3 M.Wt 464.64
Solubility ≥5.67mg/mL in DMSO with gentle warming, <2.32mg l="" in="" h2o,="" ≥15.5mg/ml="" in="" etoh="" with="" ultrasonic="" and="" warming=""> Storage Store at -20°C
Physical AppearanceA solidShipping ConditionEvaluation sample solution : ship with blue ice.All other available size:ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

U-73122 is an inhibitor of phospholipase C, phospholipase A2, and 5-LO (5-lipoxygenase).

ApexBio的3X FLAG Peptide FLAG标签系统利用与目标蛋白质1融合的短而亲水的8个氨基酸的肽段。FLAG肽与抗体M1结合。结合是钙依赖性方式2还是非依赖性3仍存在争议。该系统的缺点是单克隆抗体纯化基质不如其他基质稳定。通常,可以用特异性单克隆抗体检测小标签。为了改善对FLAG标签的检测,已经开发了3x FLAG系统。这种三级FLAG表位是亲水的,长22个氨基酸,可以检测到高达10 fmol的表达融合蛋白。激烈热球菌的带有FLAG标签的麦芽糖糊精结合蛋白已被结晶4,其晶体质量与未标记蛋白的晶体质量非常相似。 最后,可以通过用肠激酶处理去除FLAG标签,肠激酶对肽序列5的5个C末端氨基酸具有特异性。