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ApexBio/Alarelin Acetate/50mg/A3151

价格
¥11300.00
货号:A3151
浏览量:44
品牌:ApexBio
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商品描述
Related Products
  • GnRH Associated Peptide (GAP) (1-13), human
  • Leuprolide Acetate
Molarity CalculatorDilution Calculator
Alarelin AcetateSynthetic GnRH agonist

Catalog No.A3151
SizePriceStockQty
50mg
$137.00
In stock
100mg
$164.00
In stock
500mg
$411.00
In stock
1g
$565.00
In stock

Tel: +1-832-696-8203

Email: sales@apexbt.com

Worldwide Distributors

Sample solution is provided at 25 µL, 10mM.

Publications citing ApexBio Products

Nature.2017 Jan 19;541(7637):417-420.
Nature.2018 Nov;563(7731):407-411.
Nature.2018 Jun 13.
Nature.2018 Jun 27.
Nature.2018 Mar 29;555(7698):673-677.
Nature.2017 Sep 7;549(7670):96-100.
Nature.2016 Apr 21;532(7599):398-401.
Science.2016 Aug 5;353(6299)594-8
Nat Nanotechnol.2017 Dec;12(12):1190-1198.
Nature Biotechnology.2017 Jun;35(6):569-576
Nat Med.2018 Sep 17.
Cell.2018 Dec 21. pii: S0092-8674(18)31561-7.
Cell.Available online 25 October 2018.
Cell.2018 Sep 27. pii: S0092-8674(18)31183-8.
Cell.2018 Jun 28;174(1):172-186.e21.
Cell.2018 Feb 22;172(5):1007-1021.e17.
Cell.2017 Nov 30;171(6):1284-1300.e21.
Cell.2017 Aug 17. pii: S0092-8674(17)30869-3.
Cell.2017 Jul 13;170(2):312-323
Nat Med.2018 Jan 29.
Nat Med.2017 Nov;23(11):1342-1351.
Cell.2017 Apr 6;169(2):286-300.
Cell.2015 Aug 27;162(5):987-1002.
Cell.2015 Feb 12;160(4):729-44.
Nature Medicine.2017 Apr;23(4):493-500.
Cancer Cell.2018 May 14;33(5):905-921.e5.
Cancer Cell.2018 Apr 9;33(4):752-769.e8.
Cancer Cell.2018 Mar 12;33(3):401-416.e8.
Cancer Cell.2017 Aug 14;32(2):253-267.e5.
Nat Methods.2018 Jul;15(7):523-526.
Cell Stem Cell.2018 May 3;22(5):769-778.e4.
Cell Stem Cell.2017 Nov 20. pii: S1934-5909(17)30375-2.

Quality Control

Quality Control & MSDS

View current batch:
    Purity = 99.56%
  • COA (Certificate Of Analysis)
  • HPLC
  • MS(Mass Spectrometry)
  • MSDS (Material Safety Data Sheet)
  • Datasheet

Chemical structure

Alarelin Acetate

Alarelin Acetate Dilution Calculator

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Alarelin Acetate Molarity Calculator

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Chemical Properties

Cas No. 79561-22-1SDF Download SDF
Synonyms Alarelin
Chemical Name acetic acid compound with (Z)-N-((6S,7Z,9S,10Z,12R,13Z,15S,16Z,18S,19Z,21S,22Z,24S)-21-((1H-indol-3-yl)methyl)-1-amino-6-((S)-2-((Z)-(ethylimino)(hydroxy)methyl)pyrrolidine-1-carbonyl)-8,11,14,17,20,23-hexahydroxy-15-(4-hydroxybenzyl)-18-(hydroxymethyl)-2
Canonical SMILES CC/N=C(O)/[C@]1([H])CCCN1C([C@](/N=C(O)/[C@](/N=C(O)/[C@@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/C2([H])CCC(O)=N2)([H])CC3=CN=CN3)([H])CC4=CNC5=CC=CC=C45)([H])CO)([H])CC6=CC=C(O)C=C6)([H])C)([H])CC(C)C)([H])CCCNC(N)=N)=O.CC(O)=O.CC(O
Formula C60H86N16O16 M.Wt 1287.42
Solubility ≥128.8mg/mL in H2O, ≥128.7mg/mL in DMSO, ≥128.6mg/mL in EtOH Storage Store at -20°C
Physical AppearanceA solidShipping ConditionEvaluation sample solution : ship with blue ice.All other available size:ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

Alarelin (Gonadotrophin-releasing hormone) is a synthetic GnRH agonist. Alarelin is found in higher amounts than that of LH-RH in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions. Alarelin is known for its induction of ovulation and is used to treat endmometriosis. Alarelin Acetate is the acetate form of a hypothalamic peptide that stimulates the release of FSH and LH from the pituitary gland.

ApexBio的3X FLAG Peptide FLAG标签系统利用与目标蛋白质1融合的短而亲水的8个氨基酸的肽段。FLAG肽与抗体M1结合。结合是钙依赖性方式2还是非依赖性3仍存在争议。该系统的缺点是单克隆抗体纯化基质不如其他基质稳定。通常,可以用特异性单克隆抗体检测小标签。为了改善对FLAG标签的检测,已经开发了3x FLAG系统。这种三级FLAG表位是亲水的,长22个氨基酸,可以检测到高达10 fmol的表达融合蛋白。激烈热球菌的带有FLAG标签的麦芽糖糊精结合蛋白已被结晶4,其晶体质量与未标记蛋白的晶体质量非常相似。 最后,可以通过用肠激酶处理去除FLAG标签,肠激酶对肽序列5的5个C末端氨基酸具有特异性。