Details

For a detailed description of Aβ 1-42, please see product H-1368.For the preparation of Aβ for experimental use, Fezoui et al. (2000) found that solvation of synthetic peptide with sodium hydroxide (Aβ·NaOH) followed by lyophilization, produced stocks with superior solubility and fibrillogenesis characteristics. Solubilization of the pretreated material with neutral buffers resulted in a pH transition from ≈10.5 to neutral, avoiding the isoelectric point of Aβ (pI≈5.5), at which Aβ precipitation and aggregation propensity are maximal. Item Number4089802One Letter CodeDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIASynonymsAβ42 sodium saltMolecular FormulaC₂₀₃H₃₁₁N₅₅O₆₀SRelative Molecular Mass4514.10CAS Registry Number[107761-42-2] netSourceSyntheticStorage Conditions-20 ± 5 °CAreas of Interest Alzheimers DiseaseAntimicrobial & Antiviral Peptides Links / Documents:

• Peptide Calculator
• MSDS

Brochures:

• Amyloid Peptides
• Care and Handling of Amyloid Peptides

Product citations

R.H.Takahashi et al., PLoS ONE, 8, e51965 (2013) Y.Fezoui et al., Amyloid, 7, 166 (2000)

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