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蚂蚁淘在线 / 品牌中心 / Lifespan / Lifespan/Salmonella typhimurium fliC / Flagellin Protein (Native) - LS-G3927/100 µg/LS-G3927-100
商品描述
Type
Native Protein
Target
fliC / Flagellin
Species
Salmonella typhimurium
Modifications
Unmodified
Source Species
Salmonella typhimurium
Purification
Greater than 90% by SDS-PAGE
Bio-Activity
Activation of TLR5 in human epithelial cell assays based on NF-kappaB luciferase fusions, on expression of IL-8 (CXCL8), CCL20, inducible nitric oxide synthase, beta-defensin 2 and matrilysin (MMP-7). Maturation of dendritic cells in in vitro and in vivo assays. Adjuvant activity on foreign antigens delivered by subcutaneous and intranasal routes in mice. TLR5 can be stimulated in vitro by Flagellin at a concentration of 5-50ng /ml and in vivo at a starting concentration of 0.1-1µg /mouse.
Endotoxin
Less than 0.1 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from PBS
Reconstitution
Reconstitute with 100 µl sterile water.
Storage
Store lyophilized at -20°C for up to 6 months. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio GuaranteeAbout fliC / Flagellin
NP_416433.1
