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Advanced immunochemical/Monoclonal mouse anti-carcinoembryonic (CEA) antigen/0.2 mg/2-CEA

价格
¥6440.00
货号:2-CEA
浏览量:111
品牌:Advanced immunochemical
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商品描述

General Category:

    Monoclonal antibodies » Tumor Markers

Disease Category:

    Tumor Markers » Monoclonal antibodies
MAbs:
3C1, 3C6(MAb 3C8 is available under Cat.#2-CEA-iv)Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with human natural tumor-derived purified CEA antigen.
Specificity:
MAb 3C6: epitope specificity group IMAb 3C1: epitope specificity group IVa or IIEpitope specificity is given per ISOBM classification. MAbs are not cross-reacting with human leukocytes in cytofluorometry.
MAb Isotypes:
IgG1 for MAbs 3C1, 3C6
Applications:
MAbs 3C6 can be used in immunohistochemistry.MAbs 3C1 and 3C6 are working in EIA. MAbs 3C1 and 3C6 are working in Western blotting. Recommended pair for sandwich immunoassay (capture-detection): 3C6 – 3C1
Purification:
Ion exchange chromatography
Presentation:
10 mM Tris, pH 7.5, 0.15 M NaCl, 0.05% sodium azide (NaN3)
Storage Conditions:
+ 4 °C
Material Safety Note:
This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material.Contains sodium azide (0.05%) as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Advanced immunochemical高敏C反应蛋白人C反应蛋白(CRP)是所谓的急性期蛋白之一。它在血液中的浓度随着对炎症的反应而迅速增加。CRP是224个残基蛋白,单体分子量约为25 kDa,pI 6.4(1-4)。它属于五味子毒素,这是一种进化保守的蛋白质家族,其特征在于钙依赖性配体结合和五个单体的对称性,这些单体在中心孔周围形成一个环(5)。CRP在体内的确切功能尚不完全清楚。已证明CRP参与炎症以及先天免疫过程。CRP的重要生物活性取决于其与各种配体(例如受损细胞膜,凋亡细胞和纤连蛋白)的结合能力,对磷胆碱残基的亲和力最高。当CRP与配体结合时,它可以被补体成分C1q识别,从而激活经典补体途径。另一方面,CRP通过与补体因子H相互作用来调节替代补体途径