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Advanced immunochemical/Recombinant human Insulin-like growth factor binding protein 5 (IGFBP-5)/0.05 mg/8-IGBP5

价格
¥39500.00
货号:8-IGBP5
浏览量:75
品牌:Advanced immunochemical
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商品描述

General Category:

    Antigens » Tumor Markers

Disease Category:

    Tumor Markers » Antigens
Source:
Expressed in mammalian cell line
Description:
IGFBP-5 is expressed as full length mature protein (amino acids 21-272, UniProt ID = P24593).
Applications:
Suitable for use as a mass IGFBP-5 standard, standard or calibrator in immunoassay.
Analysis:
Purity > 90% (according to SDS-PAAG), including detected fragments.IGFBP-5 concentration is determined spectrophotometrically.Immunoreactivity is confirmed in sandwich immunoassay with specific monoclonal antibodies.
Purification:
Immunoaffinity purification
Presentation:
40 mM sodium citrate pH 4.0
Storage Conditions:
-70 °C (between -65 and -80 °C allowed)
Other information:
Avoid repeated freezing and thawing.It is recommended to aliquot the product after the first thawing.Store the protein at pH 4.0. Storage at other pH values may result in decrease of recombinant human IGFBP-5 immunological activity.
Material safety note:
This product is sold for research use only. Standard Laboratory Practices should be followed when handling this material.
Advanced immunochemical高敏C反应蛋白人C反应蛋白(CRP)是所谓的急性期蛋白之一。它在血液中的浓度随着对炎症的反应而迅速增加。CRP是224个残基蛋白,单体分子量约为25 kDa,pI 6.4(1-4)。它属于五味子毒素,这是一种进化保守的蛋白质家族,其特征在于钙依赖性配体结合和五个单体的对称性,这些单体在中心孔周围形成一个环(5)。CRP在体内的确切功能尚不完全清楚。已证明CRP参与炎症以及先天免疫过程。CRP的重要生物活性取决于其与各种配体(例如受损细胞膜,凋亡细胞和纤连蛋白)的结合能力,对磷胆碱残基的亲和力最高。当CRP与配体结合时,它可以被补体成分C1q识别,从而激活经典补体途径。另一方面,CRP通过与补体因子H相互作用来调节替代补体途径