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Advanced immunochemical/Monoclonal mouse anti-Diphtheria toxin/0.2 mg/1-DT1

价格
¥3980.00
货号:1-DT1
浏览量:110
品牌:Advanced immunochemical
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商品描述

General Category:

    Monoclonal antibodies » Microbial & Plant Toxins

Disease Category:

    Microbial & Plant Toxins » Monoclonal Antibodies
MAbs:
1H2, 3B6, DiD1, DiB4, DiH1Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cellsof Balb/c mice immunized with Diphtheria toxoid (MAbs 1H2, 3B6) or supernatant from C.diphtheriae (MAbs DiD1, DiB4, DiH1).
Specificity:
MAbs react with different determinants of Diphtheria toxin and anatoxin. They do not react with free A or B subunits of Diphtheria toxin..
MAb Isotypes:
IgG1 for MAbs 1H2, 3B6, DiH1IgG2b for MAbs DiD1, DiB4
Applications:
Detection of Diphtheria toxin by different immunochemical techniques.All MAbs are working in EIA. Recommended pairs for sandwich immunoassay (capture-detection):3B6 – 1H2, DiH1 – DiB4, DiH1 – DiD1MAbs DiD1 and DiB4 are working in Western blotting.
Purification:
MAbs 1H2 and 3B6 by chromatography on protein A SepharoseMAbs DiD1, DiB4 and DiH1 by chromatography on protein G Sepharose
Presentation:
PBS, pH 7.4, 0.1 % sodium azide (NaN3)
Storage Conditions:
+ 4 °C
Material Safety Note:
This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material.Contains sodium azide (0.1 %) as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Advanced immunochemical高敏C反应蛋白人C反应蛋白(CRP)是所谓的急性期蛋白之一。它在血液中的浓度随着对炎症的反应而迅速增加。CRP是224个残基蛋白,单体分子量约为25 kDa,pI 6.4(1-4)。它属于五味子毒素,这是一种进化保守的蛋白质家族,其特征在于钙依赖性配体结合和五个单体的对称性,这些单体在中心孔周围形成一个环(5)。CRP在体内的确切功能尚不完全清楚。已证明CRP参与炎症以及先天免疫过程。CRP的重要生物活性取决于其与各种配体(例如受损细胞膜,凋亡细胞和纤连蛋白)的结合能力,对磷胆碱残基的亲和力最高。当CRP与配体结合时,它可以被补体成分C1q识别,从而激活经典补体途径。另一方面,CRP通过与补体因子H相互作用来调节替代补体途径