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Advanced immunochemical/Monoclonal mouse anti-human soluble transferrin receptor, in vitro/0.2 mg/2-TR-iv

价格
¥4400.00
货号:2-TR-iv
浏览量:89
品牌:Advanced immunochemical
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商品描述

General Category:

    Monoclonal antibodies
      Monoclonal antibodies » Blood Coagulation and Anemia

Disease Category:

    Blood Coagulation and Anemia » Monoclonal AntibodiesKidney Diseases » Monoclonal AntibodiesCardiac Markers » Monoclonal antibodies » Other Cardiac Markers
MAbs:

11F5cc

Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Blab/c mice immunized with purified human soluble transferrin receptor.

Specificity:
Human soluble transferrin receptor and complex between soluble transferrin receptor and transferrin.
MAb Isotypes:

IgG2b for MAb 11F5cc

Purification:
Chromatography on protein A Sepharose
Presentation:
PBS, pH 7.4, 0.09 % sodium azide (NaN3)
Storage Conditions:

+4 °C (+2 … +8 °C allowed)

Other Information:

More antibodies against human soluble transferrin receptor under Cat# 2-TRs.

Material safety note:

This product is sold for research use only. Standard Laboratory Practices should be followed when handling this material.

Product contains sodium azide as a preservative. Although the amount sodium azide is very small appropriate card must be taken when handling this product.

References:

Search Soluble transferrin receptor, in vitro on PubMed

Advanced immunochemical高敏C反应蛋白人C反应蛋白(CRP)是所谓的急性期蛋白之一。它在血液中的浓度随着对炎症的反应而迅速增加。CRP是224个残基蛋白,单体分子量约为25 kDa,pI 6.4(1-4)。它属于五味子毒素,这是一种进化保守的蛋白质家族,其特征在于钙依赖性配体结合和五个单体的对称性,这些单体在中心孔周围形成一个环(5)。CRP在体内的确切功能尚不完全清楚。已证明CRP参与炎症以及先天免疫过程。CRP的重要生物活性取决于其与各种配体(例如受损细胞膜,凋亡细胞和纤连蛋白)的结合能力,对磷胆碱残基的亲和力最高。当CRP与配体结合时,它可以被补体成分C1q识别,从而激活经典补体途径。另一方面,CRP通过与补体因子H相互作用来调节替代补体途径