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Abeomics/Monoclonal Antibody to BEX (Clone: ABM29C7)/25 µg/10-10016

价格
¥1800.00
货号:10-10016
浏览量:127
品牌:Abeomics
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商品描述

Format :Purified
Amount :100 µg
Isotype :Mouse IgG1
Purification :Protein G Chromatography
Content :100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition :Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles
Gene :BEX1
Gene ID :55859
Uniprot ID :Q9HBH7
Alternative Name :Protein BEX1, Brain-expressed X-linked protein 1
Immunogen Information :Full length recombinant BEX protein was used as the immunogen for this antibody.

Western blot analysis- 4-6µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:Nucleus, Cytoplasm
Post transnational modification:Ubiquitinated. Degraded by the proteasome (By similarity).
Tissue Specificity:Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Expressed in lung, skeletal muscle, peripheral blood leukocyte, stomach, lymph node, trachea and bone marrow. Highly expressed in acute myeloid leukemia.
BioGrid:120961.15 interactions.
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Abeomics的人PD-L1重组Fc融合蛋白(正在供货)CHO-K1 Celline。 PD-L1(CD274 / B7-H1)是一种重要的膜结合共刺激分子,属于B7超家族,可通过其受体抑制免疫反应,PD-1和PD-L1在炎症性疾病的发病机理中起关键作用死亡1)。它在单核吞噬细胞系统(MPS)中广泛表达,可共同刺激T细胞并调节炎症反应。PD-L1通过对T细胞功能产生负面共刺激作用来发挥炎症调节功能,以抑制细胞因子分泌,促进活化T细胞凋亡并诱导T细胞无反应。在细菌感染,炎症和许多自身免疫性疾病中,已经报道了CD274的异常表达和失调。