Format : | concentrate |
Amount : | 0.5 ml |
Content : | TRIS with 0.03% sodium azide, pH7.2 |
Storage condition : | Store at 4°C |
Gene : | MCM2 |
Gene ID : | 4171 |
Uniprot ID : | P49736 |
Alternative Name : | Minichromosome maintenance protein 2 homolog, Nuclear protein BM28, BM28, CCNL1, CDCL1, KIAA0030 |
Immunohistochemical Analysis :-1:200
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Nucleus |
Post transnational modification: | Phosphorylated on Ser-108 by ATR in proliferating cells. Ser-108 proliferation is increased by genotoxic agents. Ser-40 is mediated by the CDC7-DBF4 and CDC7-DBF4B complexes, while Ser-53 phosphorylation is only mediated by the CDC7-DBF4 complex. Phosphorylation by the CDC7-DBF4 complex during G1/S phase is required for the initiation of DNA replication. |
BioGrid: | 110339.950 interactions. |
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