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Abeomics/Mouse IgG1 Isotype Control (Clone: MOPC31C)- FITC/25 µg/10-101-F

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¥1100.00
货号:10-101-F
浏览量:121
品牌:Abeomics
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商品描述

Format :Purified
Amount :100 µg
Isotype :Mouse IgG1
Purification :Affinity Chromatography
Content :0.2 mg/ml in Tris buffer containing 0.05% Azide
Storage condition :Store the Isotype control at 4°C, stable for 6 months.

A mouse isotype control is an antibody of the same class (isotype) of immunoglobulin as the specific mouse antibody, but is either myeloma-derived antibody of unknown specificity, or is raised against an antigen that is presumed not to be present on or in the cells under study. Isotype control antibodies are used for the estimation of non-specific binding of target primary antibodies to cell surface antigens.

FACS: 0.25-2 µg/10^6 cells

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Abeomics的人PD-L1重组Fc融合蛋白(正在供货)CHO-K1 Celline。 PD-L1(CD274 / B7-H1)是一种重要的膜结合共刺激分子,属于B7超家族,可通过其受体抑制免疫反应,PD-1和PD-L1在炎症性疾病的发病机理中起关键作用死亡1)。它在单核吞噬细胞系统(MPS)中广泛表达,可共同刺激T细胞并调节炎症反应。PD-L1通过对T细胞功能产生负面共刺激作用来发挥炎症调节功能,以抑制细胞因子分泌,促进活化T细胞凋亡并诱导T细胞无反应。在细菌感染,炎症和许多自身免疫性疾病中,已经报道了CD274的异常表达和失调。