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Abeomics/Polyclonal Antibody to GNPDA1/25 µg/11-12005

价格
¥1600.00
货号:11-12005
浏览量:68
品牌:Abeomics
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商品描述

Format :Purified
Amount :100 µg
Isotype :Rabbit IgG
Purification :Protein A Chromatography
Content :25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition :Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene :GNPDA1
Gene ID :10007
Uniprot ID :P46926
Alternative Name :GNPDA1, GNPI, HLN, KIAA0060
Immunogen Information :A partial length recombinant GNPDA1 protein (amino acids 13-242) was used as the immunogen for this antibody.

GNPDA1 is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium.This protein triggers calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo. GNPDA1 highest expression is found in ovary and colon and in KG-1 and HeLa cell lines.

Western blot analysis: 1-2 µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:Cytoplasm
BioGrid:115325.37 interactions.
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Abeomics的人PD-L1重组Fc融合蛋白(正在供货)CHO-K1 Celline。 PD-L1(CD274 / B7-H1)是一种重要的膜结合共刺激分子,属于B7超家族,可通过其受体抑制免疫反应,PD-1和PD-L1在炎症性疾病的发病机理中起关键作用死亡1)。它在单核吞噬细胞系统(MPS)中广泛表达,可共同刺激T细胞并调节炎症反应。PD-L1通过对T细胞功能产生负面共刺激作用来发挥炎症调节功能,以抑制细胞因子分泌,促进活化T细胞凋亡并诱导T细胞无反应。在细菌感染,炎症和许多自身免疫性疾病中,已经报道了CD274的异常表达和失调。