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商品描述
FGF 4 (NT)
fibroblast growth factor 4
Download Product PDFProduct Preparation
A synthetic peptide corresponding to the N-terminus of Fibroblast Growth Factor 4 protein. This sequence is identical to human, mouse, rat and bovine.
Background
FGF4 is a member of fibroblast growth factor (FGF) family. The FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. FGF4and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
PURIFICATION The Rabbit IgG is purified by Epitope Affinity Purification | SPECIFICITY This antibody recognizes ~~22 kDa of FGF4 protein. |
FORMULATION This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. | STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles. |
Gene ID
2249
Applications/Suggested Working Dilutions
Western Blot 0.1-1 µg/ml | ELISA 0.01-0.1 µg/ml | Immunoprecipitation 2-5µg/ml | IHC 2-10µg/ml | Flow cytometry 5-10µg/ml |
