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商品描述
CD20
MS4A1, CD20, CD20 antigen, CD20 receptor, B-Lympho
Download Product PDFProduct Preparation
A synthetic peptide corresponding to C-terminus of human CD20 protein.
Background
CD20, a non-glycosylated protein, belongs to a member of the membrane-spanning 4A gene family. The molecular weight is at a range of~34-37kDa depending on the degree of the protein phosphorylation. The CD20 antigen is present on human pre B lymphocytes and B lymphocytes at all stages of maturation. Thus, it plays an important role in the development and differentiation of B-cells into plasma cells. Low level of CD20 expression appears on normal T lymphocytes.Combination of chemo and humanized CD20 antibodies has been reported in clinical study of lymphoma diseases.
PURIFICATION The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping | SPECIFICITY This antibody recognizes ~34 kDa of human CD20.The other species are not tested |
FORMULATION This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. | STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles. |
Gene ID
931
Applications/Suggested Working Dilutions
Western Blot 0.1-1 µg/ml | ELISA 0.01-0.1 µg/ml | Immunoprecipitation 2-5µg/ml | IHC 2-10µg/ml | Flow cytometry 5-10µg/ml |