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FTH1 Human/重组人铁蛋白重链产品编号：PRO-658
产品规格：5 g/25 g/1mg Synonyms Ferritin heavy chain, Cell proliferation-inducing gene 15 protein, FTH1, FHC, FTH, PLIF, FTHL6, PIG15, MGC104426. Introduction Ferritin is a fairly large, iron-storage heteropolymeric protein composed of 2 subunit types, light Ferritin heavy Ferritin polypeptides, which is expressed in most kinds of cells ａnd co-assemble in different proportion in a tissue-specific manner. Ferritin is composed of 24 self-assembled polypeptide subunits of the heavy ａnd light ferritin chains ａnd is characterized by the capacity to remove Fe （II） from solution in the presence of oxygen.
Ferritin light polypeptide protein is the main intracellular iron storage protein in prokaryotes ａnd eukaryotes. Variation in ferritin subunit composition influence the rates of iron uptake ａnd release in various tissues. A key function of ferritin is the storage of iron in a soluble ａnd nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases ａnd hyper ferrit anemia-cataract syndrome.
Ferritin stores iron in a soluble, nontoxic, readily accessible form. Ferritin is needed for iron homeostasis. Iron is taken up in the ferrous form ａnd deposited as ferric hydroxides after it has been oxidized. Description FTH1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 183 amino acids ａnd having a molecular mass of 21 kDa. Source Escherichia Coli. Physical Appearance Sterile Filtered colorless solution. Formulation The FTH1 protein solution contains 20mM Tris-HCl pH-7.5, 1mM DTT ａnd 10% glycerol. Stability Ferritin Heavy Chain although stable 4 C for 4 weeks, should be stored desiccated below -18 C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Amino Acid Sequence MTTASTSQVR QNYHQDSEAA INRQINLELY ASYVYLSMSY YFDRDDVALK NFAKYFLHQS HEEREHAEKL MKLQNQRGGR IFLQDIKKPD CDDWESGLNA MECALHLEKN VNQSLLELHK LATDKNDPHL CDFIETHYLN EQVKAIKELG DHVTNLRKMG APESGLAEYL FDKHTLGDSD NES. Purity Greater than 95.0% as determined by SDS-PAGE. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

关键词：FTH1Human重组人铁蛋白重链

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