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Immunoway/MAP2 (phospho-Ser136) rabbit pAb/20ug 50ug 100ug/YP1390

价格
¥1700.00
货号:YP1390
浏览量:127
品牌:Immunoway
服务
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商品描述

MAP2 (phospho-Ser136) rabbit pAb

  • Catalog No.:YP1390
  • Applications:WB
  • Reactivity:Human,Rat
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • Gene Name:
    • MAP2
    • Protein Name:
    • MAP2 (Ser136)
    • Human Gene Id:
    • 4133
    • Human Swiss Prot No:
    • P11137
    • Mouse Swiss Prot No:
    • P20357
    • Rat Swiss Prot No:
    • P15146
    • Immunogen:
    • Synthesized phosho peptide around human MAP2 (Ser136)
    • Specificity:
    • This antibody detects endogenous levels ofHuman Rat MAP2 (phospho-Ser136)
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:1000-2000
    • Purification:
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Other Name:
    • Microtubule-associated protein 2 (MAP-2)
    • Observed Band(KD):
    • 200
    • Background:
    • microtubule associated protein 2(MAP2)Homo sapiensThis gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010],
    • Function:
    • alternative products:Additional isoforms seem to exist,function:The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.,PTM:MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 Tau/MAP repeats.,similarity:Contains 4 Tau/MAP repeats.,
    • Subcellular Location:
    • nucleolus,cytoplasm,microtubule,microtubule associated complex,neuron projection,
    • Expression:
    • Brain,Brain cortex,Epithelium,Pancreas,Testis,
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • June 19-2018
    • FLOW CYTOMEYRT PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    Immunoway角蛋白8(KRT8)智人该基因是II型角蛋白家族的一个成员,聚集在12号染色体的长臂上。I型和II型角蛋白在上皮细胞的细胞质中杂聚形成中等大小的细丝。该基因的产物通常与角蛋白18聚合,在简单的单层上皮细胞中形成中间丝。该蛋白在维持细胞结构完整性中起作用,并且还在信号转导和细胞分化中起作用。该基因的突变会导致隐源性肝硬化。已经发现该基因的剪接的转录变体。