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商品描述
Thrombospondin 1 Polyclonal Antibody
- Catalog No.:YT6293
- Applications:WB, ELISA
- Reactivity:Human, Mouse, Rat
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name:
- THBS1 TSP TSP1
- Protein Name:
- Thrombospondin 1
- Human Gene Id:
- 7057
- Human Swiss Prot No:
- P07996
- Immunogen:
- Synthesized peptide derived from human Thrombospondin 1
- Specificity:
- This antibody detects endogenous levels of human Thrombospondin 1
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Rabbit
- Dilution:
- WB 1:500-2000, ELISA(peptide)1:5000-20000
- Purification:
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -20°C/1 year
- Other Name:
- Thrombospondin-1
- Observed Band(KD):
- 130
- Background:
- thrombospondin 1(THBS1) Homo sapiensThe protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008],
- Function:
- function:Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1, alpha-V/beta-3 and alpha-IIb/beta-3.,similarity:Belongs to the thrombospondin family.,similarity:Contains 1 TSP C-terminal (TSPC) domain.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:Contains 1 VWFC domain.,similarity:Contains 3 EGF-like domains.,similarity:Contains 3 TSP type-1 domains.,similarity:Contains 8 TSP type-3 repeats.,subunit:Homotrimer; disulfide-linked.,
- Subcellular Location:
- extracellular region,fibrinogen complex,extracellular space,endoplasmic reticulum,endoplasmic reticulum lumen,external side of plasma membrane,cell surface,sarcoplasmic reticulum,secretory granule,extracellular matrix,platelet alpha granule,
- Expression:
- Aorta endothelial cell,Endothelial cell,Liver,Plasma,Platelet,Saliva,
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- Antibody-FAQs