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Immunoway/β-Tubulin Monoclonal Hybridoma/Hybridoma/CM3030

价格
¥60000.00
货号:CM3030
浏览量:78
品牌:Immunoway
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商品描述

β-Tubulin Monoclonal Hybridoma

  • Catalog No.:CM3030
  • Applications:WB,IF,IHC-p
  • Reactivity:Human,Rat,Mouse,Mk,Dg,Ch,Hamster,Rb,sheep,Insect,Yeast
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • Gene Name:
    • TUBB3
    • Protein Name:
    • Tubulin beta-3 chain
    • Human Gene Id:
    • 10381
    • Human Swiss Prot No:
    • Q13509
    • Immunogen:
    • Synthetic Peptide of β-Tubulin
    • Specificity:
    • This monoclonal Hybridoma can product antibody detects Tubulin beta-3 chain protein. Please see the antibody (catalog# YM3030) for more information in our website
    • Source:
    • Mouse
    • Dilution:
    • WB: 1:5000 IHC: 1:200 IF 1:200
    • Storage Stability:
    • liquid nitrogen
    • Other Name:
    • TUBB3; TUBB4; Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-III
    • Background:
    • domain:The highly acidic C-terminal region may bind cations such as calcium.,function:Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.,function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,polymorphism:Genetic variations in MC1R are associated with variation in skin/hair/eye pigmentation type 2 (SHEP2) [MIM:266300]. Hair, eye and skin pigmentation are among the most visible examples of human phenotypic variation, with a broad normal range that is subject to substantial geographic stratification. In the case of skin, individuals tend to have lighter pigmentation with increasing distance from the equator. By contrast, the majority of variation in human eye and hair color is found among individuals of European ancestry, with most other human populations fixed for brown eyes and black hair.,polymorphism:Variations in MC1R are linked to the degree of skin pigmentation (Types I-IV). Type I skin the most lightly pigmented and type IV the most dark pigmented. Partial loss-of-function mutations are associated with fair skin, poor tanning and increased skin cancer risk.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,tissue specificity:Melanocytes and corticoadrenal tissue.,
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • June 19-2018
    • FLOW CYTOMEYRT PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    Immunoway角蛋白8(KRT8)智人该基因是II型角蛋白家族的一个成员,聚集在12号染色体的长臂上。I型和II型角蛋白在上皮细胞的细胞质中杂聚形成中等大小的细丝。该基因的产物通常与角蛋白18聚合,在简单的单层上皮细胞中形成中间丝。该蛋白在维持细胞结构完整性中起作用,并且还在信号转导和细胞分化中起作用。该基因的突变会导致隐源性肝硬化。已经发现该基因的剪接的转录变体。