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Immunoway/WIPI2 (phospho-Ser413) rabbit pAb/20ug 50ug 100ug/YP1552

价格
¥1700.00
货号:YP1552
浏览量:85
品牌:Immunoway
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商品描述

WIPI2 (phospho-Ser413) rabbit pAb

  • Catalog No.:YP1552
  • Applications:WB
  • Reactivity:Human,Mouse,Rat
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • Gene Name:
    • WIPI2 CGI-50
    • Protein Name:
    • WIPI2 (Ser413)
    • Human Gene Id:
    • 26100
    • Human Swiss Prot No:
    • Q9Y4P8
    • Mouse Gene Id:
    • 74781
    • Mouse Swiss Prot No:
    • Q80W47
    • Rat Gene Id:
    • 288498
    • Rat Swiss Prot No:
    • Q6AY57
    • Immunogen:
    • Synthesized phosho peptide around human WIPI2 (Ser413)
    • Specificity:
    • This antibody detects endogenous levels ofHuman Mouse Rat WIPI2 (phospho-Ser413)
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:1000-2000
    • Purification:
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Other Name:
    • WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2)
    • Observed Band(KD):
    • 49
    • Background:
    • WD repeat domain, phosphoinositide interacting 2(WIPI2) Homo sapiensWD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008],
    • Function:
    • similarity:Contains 3 WD repeats.,tissue specificity:Ubiquitously expressed. Highly expressed in heart, skeletal muscle and pancreas. Expression is down-regulated in pancreatic and in kidney tumors.,
    • Subcellular Location:
    • pre-autophagosomal structure,nucleoplasm,cytoplasm,autophagosome,cytosol,membrane,extrinsic component of membrane,pre-autophagosomal structure membrane,protein complex,
    • Expression:
    • Esophagus tumor,Placenta,Skin,Testis,Thalamus,
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • June 19-2018
    • FLOW CYTOMEYRT PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    Immunoway角蛋白8(KRT8)智人该基因是II型角蛋白家族的一个成员,聚集在12号染色体的长臂上。I型和II型角蛋白在上皮细胞的细胞质中杂聚形成中等大小的细丝。该基因的产物通常与角蛋白18聚合,在简单的单层上皮细胞中形成中间丝。该蛋白在维持细胞结构完整性中起作用,并且还在信号转导和细胞分化中起作用。该基因的突变会导致隐源性肝硬化。已经发现该基因的剪接的转录变体。