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Immunoway/DAPP1/BAM32 (phospho-Tyr139) rabbit pAb/20ug 50ug 100ug/YP1310

价格
¥1700.00
货号:YP1310
浏览量:90
品牌:Immunoway
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商品描述

DAPP1/BAM32 (phospho-Tyr139)rabbit pAb

  • Catalog No.:YP1310
  • Applications:WB
  • Reactivity:Human
  • Data Sheet
  • MSDS
  • Support
  • Description
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  • Protocol
    • Gene Name:
    • DAPP1 BAM32 HSPC066
    • Protein Name:
    • DAPP1/BAM32 (Tyr139)
    • Human Gene Id:
    • 27071
    • Human Swiss Prot No:
    • Q9UN19
    • Mouse Gene Id:
    • 26377
    • Mouse Swiss Prot No:
    • Q9QXT1
    • Immunogen:
    • Synthesized phosho peptide around human DAPP1 (Tyr139)
    • Specificity:
    • This antibody detects endogenous levels ofHuman DAPP1 or BAM32 (phospho-Tyr139)
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:1000-2000
    • Purification:
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Other Name:
    • Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (hDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa)
    • Observed Band(KD):
    • 32
    • Function:
    • function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.,induction:Upon B-cell activation.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH2 domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation.,subunit:Interacts with PtdIns(3,4,5)P3 and PLCG2. In vitro, interacts with PtdIns(3,4)P2.,tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.,
    • Subcellular Location:
    • cytosol,plasma membrane,
    • Expression:
    • Lymph node,Umbilical cord blood,Urinary bla
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • June 19-2018
    • FLOW CYTOMEYRT PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    Immunoway角蛋白8(KRT8)智人该基因是II型角蛋白家族的一个成员,聚集在12号染色体的长臂上。I型和II型角蛋白在上皮细胞的细胞质中杂聚形成中等大小的细丝。该基因的产物通常与角蛋白18聚合,在简单的单层上皮细胞中形成中间丝。该蛋白在维持细胞结构完整性中起作用,并且还在信号转导和细胞分化中起作用。该基因的突变会导致隐源性肝硬化。已经发现该基因的剪接的转录变体。