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0512-67156496
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商品描述
DAPP1/BAM32 (phospho-Tyr139)rabbit pAb
- Catalog No.:YP1310
- Applications:WB
- Reactivity:Human
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name:
- DAPP1 BAM32 HSPC066
- Protein Name:
- DAPP1/BAM32 (Tyr139)
- Human Gene Id:
- 27071
- Human Swiss Prot No:
- Q9UN19
- Mouse Gene Id:
- 26377
- Mouse Swiss Prot No:
- Q9QXT1
- Immunogen:
- Synthesized phosho peptide around human DAPP1 (Tyr139)
- Specificity:
- This antibody detects endogenous levels ofHuman DAPP1 or BAM32 (phospho-Tyr139)
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Rabbit
- Dilution:
- WB 1:1000-2000
- Purification:
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -20°C/1 year
- Other Name:
- Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (hDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa)
- Observed Band(KD):
- 32
- Function:
- function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.,induction:Upon B-cell activation.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH2 domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation.,subunit:Interacts with PtdIns(3,4,5)P3 and PLCG2. In vitro, interacts with PtdIns(3,4)P2.,tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.,
- Subcellular Location:
- cytosol,plasma membrane,
- Expression:
- Lymph node,Umbilical cord blood,Urinary bla
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